The Swiss squandered seven set points in the opener and although he took the second on a tiebreak he capitulated in the decider after dropping serve at 1-2, losing 7-5, 6-7(3), 6-1.
Images from Day 9 of the 2021 US Open in New York on Wednesday.
The Swiss snapped a five-year barren run at the slams by bagging the Australian Open and Wimbledon titles this year and, in the absence of Novak Djokovic, Andy Murray and Stan Wawrinka, is the favourite at Flushing Meadows with an equally resurgent Rafael Nadal.
Defending champion Andy Murray eased into the Wimbledon quarter-finals for the 10th successive year with a 7-6(1), 6-4, 6-4 victory over Benoit Paire on Monday.
Novak Djokovic extended his unbeaten start to the season to 15 matches as he swatted aside German veteran Philipp Kohlschreiber 6-3 6-1 with ease on Wednesday to reach the Dubai Tennis Championships quarter-finals.
Serena Williams battered Anastasia Pavlyuchenkova 6-4, 6-4 in the quarter-finals at Wimbledon on Tuesday, seizing on moments of weakness from the Russian to ram home her advantage.
The 32-year-old, five-times a winner of the singles at the prestigious Wimbledon warm-up event, delighted a large evening centre court crowd with some fluent shot-making as he and Spanish veteran Lopez beat top seeds Juan Sebastian Cabal and Robert Farah 7-6(5), 6-3.
Cilic marches past Querrey into Queen's semis
Andy Murray proved himself the bastion of British tennis once again as he outclassed Canadian powerhouse Milos Raonic to claim a second Wimbledon title in masterful fashion on Sunday.
Taiwan's Hsieh Su-wei has enjoyed double good fortune at Melbourne Park this week.
Images from Day 1 of the 2022 US Open at the USTA Billie Jean King National Tennis Center, in Flushing Meadows, New York, on Monday.
Images from Day 3 of the 2022 Australian Open in Melbourne on Wednesday.
A year after Andy Murray's reign as Wimbledon champion ended lamely at the hands of a man dubbed the new Roger Federer, he got a stark reminder on Friday that the original is the real threat to his grand slam ambitions.
"Specifically, with Bouchard we are comfortable with our decision of putting her on Ashe, there are a lot of matches to schedule today, things could have gone many different ways," USTA spokesman Chris Widmaier told Reuters.
Images from Day 9 of the 2022 Australian Open, at Melbourne Park, on Tuesday.
Less than a month after her run to the Wimbledon final, where she lost to Spain's Garbine Muguruza, 37-year-old Williams again had to turn back time against a young challenger.
A summary of Novak Djokovic's rise in the tennis circuit in photos.
Juan Martin Del Potro, world number 165, was feeling "so alive" that by the time the match hit the mid-way point of the second set, Stan Wawrinka did not know what had hit him.
Women's tennis's biggest names still remaining at the US Open take centre stage on Sunday with Grand Slam winners Maria Sharapova, Venus Williams, Garbine Muguruza and Petra Kvitova all appearing on Arthur Ashe Stadium.
Earning his fourth straight win over a top-10 player this week, Khachanov, whose muscular game resembles that of his childhood hero Marat Safin, a Russian three-times winner in Paris, picked up the biggest title of his burgeoning career.
The Tennis Point Exhibition Series in Germany is taking place without spectators, line judges and ball kids and there are no handshakes after the match. Players arrive alone and have their own designated space in the venue to prepare. Once on court they sit at opposite sides during the changeovers.
Federer, who skipped the French Open this year to give his body time to recover from his incredible exploits in the first half of the season which he began by winning an 18th major at the Australian Open, said he hoped Murray would not live to regret battling through the pain barrier.
The lanky wild card kissed the Montreal court after completing a rousing 3-6, 6-4, 7-6(4) triumph as the 18-year-old became the youngest player to ever reach the quarter-finals of an ATP Masters 1000 event.
The 23-times Grand Slam champion looked a completely different player from the person who smashed her way into the semi-finals of the doubles with Caroline Wozniacki on Wednesday but managed to do just enough to beat the 86th-ranked McHale.
Audacious coups by Andy Murray and Angelique Kerber have transformed the tennis landscape and they will begin 2017 eyeing the kind of domination that few would have thought possible at the start of a seismic year.
A summary of sports events and sports persons, who made news on Wednesday
Once the immediate euphoria of winning Wimbledon for a second time had subsided, the tears flowing down Andy Murray's face bore testament to the sheer relief surging through his body.
'Right now I think that I have to find to myself again and just trying to forget the clay court season as soon as possible'
Top seed Roger Federer will challenge for a ninth Halle Open title after reaching the Wimbledon warm-up event final with a 6-4 7-6(5) victory over rising Russian talent Karen Khachanov on Saturday.
The United States Tennis Association (USTA) will reveal plans to build a retractable roof over the centre court at Arthur Ashe Stadium as part of major changes to the U.S. Open venue in Flushing Meadows.
It was a routine win for top seed Novak Djokovic, but his satisfaction at reaching the Wimbledon quarter-finals without dropping a set was mixed with relief after some tricky moments against German veteran Tommy Haas on Monday.
However, the 30-year-old Russia belied her own self-doubt with an impressive three-set win over the Romanian to thrust the former world number one back into the spotlight as the toast of the Big Apple.
Spain did not need their best players to beat India but then they are taking the World Group Davis Cup play-off tie very "seriously", bringing a strong 20-member contingent to tackle the lower-ranked home players.
'Right now I'm focused on going to sleep tonight and winning the next Uno match and then tomorrow we focus back on practice and then get ready for the quarter-finals.'
Dhruv Munjal on why Novak Djokovic may yet win that highly contested title.
IMAGES from Australian Open matches played at Melbourne Park on Friday
Bernard Tomic bowed out of the Australian Open on Sunday with a stinging rebuke of the scheduling.
Nadal, playing his first match since losing to Roger Federer in the Wimbledon semi-finals, fell behind 5-2 in the tiebreak before roaring back to prevail in his first career meeting with world number 53 Evans.
US tennis powerhouse Serena Williams dispatched France's Alize Cornet in two sets on Monday, ending a streak of weak family performances that saw older sister Venus eliminated from singles on Saturday and the pair knocked out in doubles on Sunday.
Former Wimbledon champion Marion Bartoli just wants to enjoy herself and play big matches when she returns to competitive tennis in March after more than four years in retirement.